Hasham @ Hisam, Rosnani and Abd. Aziz, Azila and Aziz, Ramlan and Rosli, Nur Ayshah (2015) Formulation and characterization of nanostructured lipid carrier encapsulated zingiber zerumbet oil using ultrasonication technique. Journal Of Advanced Research In Applied Mechanics, 11 (1). pp. 16-23. ISSN 2289-7895
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Official URL: https://www.akademiabaru.com/doc/ARAMV11_N1_P16_23...
Abstract
This study presents the formulation of nanostructured lipid carrier encapsulated Zingiber zerumbet oil (NLC-ZZ) using ultrasonication technique. NLC is the blend of solid lipid, liquid lipid and surfactant for encapsulation of poor water soluble actives. The NLC-ZZ formulation was characterized with respect to particle size, polydispersity index (PDI), zeta-potential, encapsulation efficiency and physical morphology. The NLC-ZZ formulation had an average diameter of 96.59 nm, PDI of 0.192, zeta-potential of -39.88 mV, and encapsulation efficiency of 90%, respectively. The NLC formulation for Zingiber zerumbet oil encapsulation has been successfully developed and is suitable for transdermal delivery system due to their nano-size and stability.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Drug delivery, Nanostructured lipid carrier |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Science |
| ID Code: | 60246 |
| Deposited By: | Haliza Zainal |
| Deposited On: | 24 Jan 2017 02:54 |
| Last Modified: | 06 Apr 2022 05:48 |
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