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Flux declination of various transmembrane pressure during cyclodextrins bioseparation

A. M., Mimi Sakinah and Ismail, Ahmad Fauzi and Hassan, Osman and Zularisam, A. W. and Md. Illias, Rosli (2007) Flux declination of various transmembrane pressure during cyclodextrins bioseparation. In: 21st Symposium of Malaysian Chemical Engineers SOMChE 2007, 12th-14th December 2007, Universiti Putra Malaysia.

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Abstract

Membrane technology is one of the separation methods which are widely used in biotechnology industries. The integration of membrane technology and an enzymatic reactor is known as an Enzymatic Membrane Reactor (EMR). EMR is widely used in fermentations, enzyme-catalyzed reactions and biotranformations. EMR can also be applied in the production of cyclodextrins (CDs). CDs are produced from starch via cyclization or intramolecular transglycosylation of the cyclodextrin glucosyltransferase (CGTase). This specialty chemical have a wide range of applications in food, pharmaceutical and chemical industries, agricultural and environmental engineering. Although EMR is a clean and environmental friendly technology, the application of membrane technology in EMR is still limited. This is due to the flux declination which is one of the significant factor that can hinder the application of membrane. This declination of flux was found to reduce the membrane productivity as well as affecting its separation performance. Thus, the main objective of this research is to determine the declination of flux during CDs production at various applied transmembrane pressure (TMP). The experiment employed hollow fiber ultrafiltration membrane to separate CDs from the reaction mixture. The experimental results show that the flux rapidly declined at high TMP. This is due to the deposition of cake on the membrane surface and within pores matrix during CDs separation process.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:Cyclodextrins, EMR, hollow fiber membrane, flux declination, TMP
Subjects:T Technology > T Technology (General)
Divisions:Chemical and Natural Resources Engineering (Formerly known)
ID Code:5742
Deposited By: Norhani Jusoh
Deposited On:03 Aug 2008 07:34
Last Modified:01 Jun 2010 15:34

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