Tan, Jully and Foo, Dominic Chwan Yee and Kumaresan, Sivakumar and Abdul Aziz, Ramlan (2005) Evaluation of pharmaceutical cream production debottlenecking schemes. In: International Symposium On Design, Operation and Control Of Chemical Processes 2005, 13-15 August 2005, Seoul, Korea.
The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increase of the product demand of 150% in the market. By carrying out throughput analysis study, schemes that fulfil the debottlenecking objective were determined. Out of the four debottlenecking schemes, Scheme 4 was chosen, which proposed a new blending tank and intermediate tank, showed a production increase of over 150%.
|Item Type:||Conference or Workshop Item (Paper)|
|Uncontrolled Keywords:||Batch, modelling, optimisation, throughput, scheduling|
|Subjects:||T Technology > T Technology (General)|
|Divisions:||Chemical and Natural Resources Engineering (Formerly known)|
|Deposited By:||Norhani Jusoh|
|Deposited On:||31 Mar 2008 09:09|
|Last Modified:||01 Jun 2010 15:29|
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