Ahmad, Farediah and Emrizal, Emrizal and M.Sirat, Hasnah and Jamaludin, Fadzureena and Mustapha, Nik Musa’adah and M.Ali, Rasadah and Arbain, Dayar and Aboul-Enein, Hassan Y. (2014) Antimicrobial and anti-inflammatory activities of Piper porphyrophyllum (Fam. Piperaceae). Arabian Journal of Chemistry, 7 (6). pp. 1031-1033. ISSN 1878-5352
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Official URL: https://doi.org/10.1016/j.arabjc.2010.12.032
Abstract
The crude extracts and isolated compounds of Piper porphyrophyllum (Piperaceae) were evaluated for antibacterial and anti-inflammatory activities. The ethyl acetate extract and 3′,4′,5,7-tetramethoxyflavone exhibited the highest activity against Staphylococcus aureus giving values of MIC = 62.5 and 250 μg/mL, respectively. 5-Hydroxy-7-methoxyflavanone and 4′,5-dihydroxy-3′,7-dimethoxyflavone were active against Pseudomonas aeruginosa, both with MIC value 125 μg/mL. The hexane extract and 4′,5-dihydroxy-3′,7-dimethoxyflavone gave the highest anti-inflammatory activity in in vitro quantitative lipoxygenase inhibition assay with inhibitory activity of (IE) 99.72% and 91.81%, respectively.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Piper porphyrophyllum extracts, flavonoids, antibacterial, anti-inflammatory |
| Subjects: | Q Science |
| Divisions: | Science |
| ID Code: | 51873 |
| Deposited By: | Siti Nor Hashidah Zakaria |
| Deposited On: | 01 Feb 2016 03:52 |
| Last Modified: | 27 Aug 2018 03:41 |
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