Dev, Selvi and Prabhakaran, Praseetha and Filgueira, Luis and Iyer, K. Swaminathan and Raston, Colin L. (2012) Microfluidic fabrication of cationic curcumin nanoparticles as an anti-cancer agent. Nanoscale, 4 (8). pp. 2575-2579. ISSN 2040-3364
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Official URL: http://dx.doi.org/10.1039/c2nr11502f
Abstract
Curcumin nanoparticles of less than 50 nm in diameter are accessible using a continuous flow microfluidic rotating tube processor (RTP) under scalable conditions, at room temperature. A mixture of DDAB and Pluronic F127 renders higher stability of the curcumin nanoparticles in physiological pH 7.4 for up to eight hours. The nanoparticles have enhanced cytotoxicity in estrogens receptor negative and positive breast cancer cell lines compared with free curcumin.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | curcumin, cancer theraphy, cytotoxicity |
| Subjects: | T Technology > TA Engineering (General). Civil engineering (General) |
| Divisions: | Biosciences and Bioengineering |
| ID Code: | 47211 |
| Deposited By: | Narimah Nawil |
| Deposited On: | 22 Jun 2015 05:56 |
| Last Modified: | 31 Mar 2019 08:34 |
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