Laser induced Coulomb explosion of gold nanoparticles : potential role for nanophotolysis of breast cancer

Abstract

Gold nano-particles are the most capable competitors for nano-photolysis such particles have adjustable optical properties, harmless, simply conjugated to antibodies. High intensity femto-second laser pulse matter interaction has let slipped a new host of phenomena with remarkable potential applications especially in nano-photolysis. Present article investigates the Coulomb explosion of gold nano-particles using laser in selective nano-photolysis of breast cancer tumor. A simulation study has been carried out to probe the conduct of nano-bullets on the basis of Coulomb explosion principle. The method illustrated here has some potential for finding the most favorable temporal and spatial confinement of laser parameters with the utilization of spherical gold nano-particles in therapeutics of cancer modalities particularly in breast cancer.