Construction of a digital resource information and diagnostic tool for brain diseases

Abstract

Brain Disease Knowledgebase (http://birg1.fbb.utm.my/bddb) is a novel comprehensive database of the 62 brain diseases. Different types of brain diseases information were determined from online survey and existing databases comparison. Biomarker, drug and protein data were mined from various scientific databases via different approaches such as web services and Perl script. Dementia diagnostic platform was designed in two types, web-based and android-based, from digitalisation of three common-used screening tests that are originally distributed by medical professionals. The data mined and diagnosis platform were then processed to form content to display. After webpage layout was designed, Brain Disease Knowledge Database (BDDB) is completed. The availability of BDDB will provide accurate information to the general public and act as a valuable knowledge vault to assist research in brain diseases. Users are able to automatically retrieve updated information, publications and statistics on brain diseases. BDDB has novel scientific data consisting of disease biomarkers and clinical methodologies. The data have been organized into different user types suitable for general public, medical professionals and scientific researchers. The Database is integrated with the digitized diagnostic tools approved by certified medical doctors, enabling fast self-accessed preliminary dementia diagnosis which is also accessible through mobile platform.