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Antioxidant, total phenolic content and cytotoxicity evaluation of selected Malaysian plants

Qader, Suhailah Wasman and Abdulla, Mahmood Ameen and Chua, Lee Suan and Najim, Nigar and Mat Zain, Mazatulikhma and Hamdan, Salehhuddin (2011) Antioxidant, total phenolic content and cytotoxicity evaluation of selected Malaysian plants. Molecules, 16 (4). pp. 3433-3443. ISSN 1420-3049

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Official URL: http://dx.doi.org/10.3390/molecules16043433

Abstract

Aqueous and ethanol extracts of different traditional Malaysian plants (Polygonum minus, Andrographis paniculata, Curcuma xanthorrhiza, Momordica charantia and Strobilanthes crispus) were evaluated for their antioxidant properties, total phenolic content and cytotoxic activity. Antioxidant activity was evaluated by using 1,1-diphenyl-1- picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays. The results showed that ethanol extracts contain high antioxidant activities compared to aqueous extracts. The findings exhibited a strong correlation between antioxidant activity and the total phenol contents. In addition, all the plant extracts showed non-toxic effects against a normal human lung fibroblast cell line (Hs888Lu). Although traditionally aqueous extracts are used, we determined that ethanol extracts usually achieved better activity in the assays.

Item Type:Article
Uncontrolled Keywords:antioxidant activity, total phenolic content, cytotoxicity, Malaysian plants
Subjects:Q Science > QD Chemistry
Divisions:Chemical Engineering
ID Code:28828
Deposited By: Liza Porijo
Deposited On:29 Nov 2012 06:25
Last Modified:29 Nov 2012 06:25

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