Ahmad, Farediah and Emrizal, Emrizal and Mohd. Sirat, Hasnah and Jamaludin, F. and Mustapha, N. M. and Ali, R. M. and Arbain, D. and Aboul, Enei (2011) Antimicrobial and anti-inflammatory activities of piper porphyrophyllum (Fam. Piperaceae). Arabian Journal of Chemistry . 001-003. ISSN 1878-5352
Official URL: http://dx.doi.org/10.1016/j.arabjc.2010.12.032
The crude extracts and isolated compounds of Piper porphyrophyllum (Piperaceae) were evaluated for antibacterial and anti-inflammatory activities. The ethyl acetate extract and 3',4',5,7-tetramethoxyflavone exhibited the highest activity against Staphylococcus aureus giving values of MIC = 62.5 and 250 µg/mL, respectively. 5-Hydroxy-7-methoxyflavanone and 4',5-dihydroxy-3',7-dimethoxyflavone were active against Pseudomonas aeruginosa, both with MIC value 125 µg/mL. The hexane extract and 4',5-dihydroxy-3',7-dimethoxyflavone gave the highest anti-inflammatory activity in in vitro quantitative lipoxygenase inhibition assay with inhibitory activity of (IE) 99.72% and 91.81%, respectively.
|Uncontrolled Keywords:||piper porphyrophyllum, extracts, flavonoids, antibacterial, anti-inflammatory|
|Deposited By:||Liza Porijo|
|Deposited On:||23 Nov 2012 08:03|
|Last Modified:||23 Nov 2012 08:03|
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