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Monoclonal IGG production and its purification challenges

Abdul Majid, Fadzilah Adibah and Loh, Melissa (2006) Monoclonal IGG production and its purification challenges. In: Special Topics In Bioprocess Engineering Volume I. Penerbit UTM, Johor , pp. 137-165. ISBN 978-983-52-0600-9

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Official URL: http://www.penerbit.utm.my/bookchapterdoc/FKKKSA/b...


B-cells are the major cells involved in the creation of antibodies that circulate in blood plasma and lymph, known as humoral immunity. B-cells, like T-cells, have surface receptors which enable them to recognize the appropriate antigen, but do not they interact to neutralize or destroy the antigen. On recognition of the antigen they take up residence in secondary lymphoid tissue and proliferate to form daughter lymphocytes, processed in the same way as them. These B-cells then develop into short-lived plasmas. The plasma cells produce antibodies and release them into the circulation at the lymph nodes. Some of the activated Bcells do not become plasma cells but instead turn into memory cells which continue to produce small amounts of the antibody long after the infection has been overcome.

Item Type:Book Section
Divisions:Chemical and Natural Resources Engineering (Formerly known)
ID Code:25685
Deposited By: Mrs Liza Porijo
Deposited On:25 May 2012 04:02
Last Modified:05 Feb 2017 03:16

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