Ibrahim, W. A. W. and Hermawan, Dadan and Sanagi, M. M. (2010) Chiral separation of econazole using micellar electrokinetic chromatography with hydroxypropyl-gamma-cyclodextrin. Journal of Pharmaceutical and Biomedical Analysis, 53 (5). 1244 - 1249.
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Official URL: http://dx.doi.org/10.1007/978-1-62703-263-6_22
Abstract
The separation of enantiomers is one of the important fi elds of modern analytical chemistry, especially for agrochemical and pharmaceutical products because the stereochemistry has a signi fi cant in fl uence on the biological activities of compounds. Cyclodextrin-modi fi ed micellar electrokinetic chromatography (CD-MEKC) has become an important capillary electrophoresis mode for enantioseparations. Here, we describe an example of a CD-MEKC method using hydroxypropyl- ? -cyclodextrin as chiral selector and sodium dodecyl sulfate as micellar solution for enantioseparation of triazole fungicides and the drug econazole.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | chromatography, electrophoresis, econazole |
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Science |
| ID Code: | 22959 |
| Deposited By: | Narimah Nawil |
| Deposited On: | 26 Feb 2017 03:16 |
| Last Modified: | 21 Oct 2018 04:29 |
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