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Effect of variable solvents on particle size of Geranium Oil-Loaded Solid Lipid Nanoparticle (Ge-SLN) for mosquito repellent applications

Asnawi, Syalwati and Aziz, Azila A. and Azizz, Rahman A. (2008) Effect of variable solvents on particle size of Geranium Oil-Loaded Solid Lipid Nanoparticle (Ge-SLN) for mosquito repellent applications. In: Nanoscience and Nanotechnology. AIP Conference Proceedings, 1136 . Amer Inst Physics , pp. 6-10. ISBN 978-0-7354-0673-5

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Abstract

A new delivery system for insect repellent is proposed by the incorporation of geranium oil into solid lipid nanoparticle (SLN). A variety of solvents which act as co-surfactants, were introduced to increase the particle size of GE-SLN. Ethanol, which has a high boiling point and a long chain alcohol produced larger particle than dichloromethane. The structure of SLN was not stable when methanol and acetone were used as co-solvents. Concentration of solvents can also influence the size of SLN. In vitro release experiments showed that SLN was able to reduce the rapid evaporation of geranium oil

Item Type:Book Section
Additional Information:Conference: International Conference on Nanoscience and Nanotechnology (NANO-SciTech 2008); Location: Selangor, Malaysia; Date : NOV 18-21, 2008; ISSN : 0094-243X
Uncontrolled Keywords:geranium oil, solid lipid nanoparticle, cosurfactant, particle size
Subjects:Q Science > QC Physics
Divisions:Science
ID Code:13745
Deposited By: Zalinda Shuratman
Deposited On:26 Aug 2011 04:49
Last Modified:07 Sep 2017 03:26

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