Harliansyah, Harliansyah and Murad, Noor Azian and Wan Ngah, Wan Zurinah and Mohd. Yusof, Yasmin Anum (2009) Antiproliferative, antioxidant and apoptosis effects of Zingiber Officenale and 6-Gingerol on HepG2 cells. Asian Journal of Biochemistry, 2 (6). pp. 421-426. ISSN 1815-9923
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Official URL: http://dx.doi.org/10.3923/ajb.2007.421.426
The present study was designed to compare the antioxidant, antiproliferative and apoptosis effects of ethanolic extract of ginger (Zingiber officinale) with its phenolic component (6)-Gingerol on human hepatoma cell line (HepG2). We found that cytotoxic and antiproliferative effect of ginger extract and (6)-Gingerol could be associated with induction of apoptosis. Both ginger extract and (6)-Gingerol also showed remarkable antioxidant activities in comparison with ascorbic acid and N-acetyl-L-cysteine.
|Uncontrolled Keywords:||antioxidant, antiproliferation, 6-Gingerol, HepG2, Zingiber Officenale|
|Subjects:||Q Science > QK Botany|
R Medicine > RV Botanic, Thomsonian, and eclectic medicine
|Deposited By:||Siti Anisa Abdul Hamid|
|Deposited On:||14 Jan 2011 01:11|
|Last Modified:||17 Jan 2011 09:37|
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