Nordin, Abu Hassan and Muhamad, Siti Nur Husna and Ahmad, Zuliahani and Nordin, Muhammad Luqman and Ahmad Ilyas, Rushdan and Azemi, Ahmad Khusairi and Ismail, Noraznawati and Nordin, Siti Hawa and Ngadi, Norzita and Mohd. Azami, Mohammad Saifulddin and Mohamad Norpi, Abdin Shakirin and Reduan, Mohd. Farhan Hanif and Osman, Abdinasir Yusuf and A. Pratama, Dyah Ayu Oktavianie and Nabgan, Walid and Shaari, Rumaizi (2023) Natural polymeric composites derived from animals, plants, and microbes for vaccine delivery and adjuvant applications: A review. Gels, 9 (3). pp. 1-28. ISSN 2310-2861
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Official URL: http://dx.doi.org/10.3390/gels9030227
Abstract
A key element in ensuring successful immunization is the efficient delivery of vaccines. However, poor immunogenicity and adverse inflammatory immunogenic reactions make the establishment of an efficient vaccine delivery method a challenging task. The delivery of vaccines has been performed via a variety of delivery methods, including natural-polymer-based carriers that are relatively biocompatible and have low toxicity. The incorporation of adjuvants or antigens into biomaterial-based immunizations has demonstrated better immune response than formulations that just contain the antigen. This system may enable antigen-mediated immunogenicity and shelter and transport the cargo vaccine or antigen to the appropriate target organ. In this regard, this work reviews the recent applications of natural polymer composites from different sources, such as animals, plants, and microbes, in vaccine delivery systems.
Item Type: | Article |
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Uncontrolled Keywords: | adjuvant, animal, microbe, natural polymer, plant, vaccine delivery |
Subjects: | T Technology > TP Chemical technology |
Divisions: | Chemical and Energy Engineering |
ID Code: | 107225 |
Deposited By: | Widya Wahid |
Deposited On: | 28 Aug 2024 07:03 |
Last Modified: | 28 Aug 2024 07:03 |
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