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Optimization of process parameters of immobilized escherichia coli for cyclodextrin production.

Mohd. Zakaria, Nur Nadia and Che Man, Rohaida and Sulaiman, Siti Zubaidah and Abdul Mudalip, Siti Kholijah and Abdul Manas, Nor Hasmaliana and Yamani, Laura Navika (2023) Optimization of process parameters of immobilized escherichia coli for cyclodextrin production. Journal of Advanced Research in Applied Mechanics, 107 (1). pp. 1-10. ISSN 2289-7895

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Official URL: http://dx.doi.org/10.37934/aram.107.1.110

Abstract

The growing interest toward cylclodectrin (CD) application in industries is due to its unique structure that able to form inclusion complexes with substances. However, the problems arise during the CD synthesis using the commercial enzyme (cyclodextrin glucanotransferase) are low production rate and the process is expensive. Hence, cell immobilization system was used. The objective of this study is to optimize the process parameters using Response Surface Methodology to increase the CD production of the immobilized cell. High CD production was achieved after the optimization process. The reusability of immobilized cell also can be reuse up to six cycles using the optimized parameters. The findings propose that optimization process increased the CD production and made it more valuable for industrial application.

Item Type:Article
Uncontrolled Keywords:biocatalyst; Cell immobilization; Cyclodextrin; Escherichia coli; process parameter.
Subjects:T Technology > TP Chemical technology
Divisions:Chemical and Energy Engineering
ID Code:106047
Deposited By: Muhamad Idham Sulong
Deposited On:29 May 2024 06:50
Last Modified:29 May 2024 06:50

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