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Prebiotics in new-born and children's health

Selvamani, Shanmugaprakasham and Kapoor, Nidhi and Ajmera, Arun and El Enshasy, Hesham Ali and Dailin, Daniel Joe and Dalia Sukmawati, Dalia Sukmawati and Abomoelak, Mona and Muktiningsih Nurjayadi, Muktiningsih Nurjayadi and Abomoelak, Bassam (2023) Prebiotics in new-born and children's health. Microorganisms, 11 (10). pp. 1-22. ISSN 2076-2607

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Official URL: http://dx.doi.org/10.3390/microorganisms11102453

Abstract

At present, prebiotics, like probiotics, are receiving more attention as a promising tool for health maintenance. Many studies have recognized the role of prebiotics in preventing and treating various illnesses including metabolic disorders, gastrointestinal disorders, and allergies. Naturally, prebiotics are introduced to the human body in the first few hours of life as the mother breastfeeds the newborn. Prebiotic human milk oligosaccharides (HMOs) are the third largest constituent of human breastmilk. Studies have proven that HMOs modulate an infant’s microbial composition and assist in the development of the immune system. Due to some health conditions of the mother or beyond the recommended age for breastfeeding, infants are fed with formula. Few types of prebiotics have been incorporated into formula to yield similar beneficial impacts similar to breastfeeding. Synthetic HMOs have successfully mimicked the bifidogenic effects of breastmilk. However, studies on the effectiveness and safety of consumption of these synthetic HMOs are highly needed before massive commercial production. With the introduction of solid foods after breastfeeding or formula feeding, children are exposed to a range of prebiotics that contribute to further shaping and maturing their gut microbiomes and gastrointestinal function. Therefore, this review evaluates the functional role of prebiotic interventions in improving microbial compositions, allergies, and functional gastrointestinal disorders in children.

Item Type:Article
Uncontrolled Keywords:breastmilk, complementary feeding, formula, human milk oligosaccharides, prebiotics, weaning
Subjects:Q Science > Q Science (General)
Divisions:Chemical and Energy Engineering
ID Code:105818
Deposited By: Yanti Mohd Shah
Deposited On:20 May 2024 06:38
Last Modified:20 May 2024 06:38

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