Mohammed Bello, Mohammed Bello and Abdullah, Faizuan and Mohd. Yusoff, Abdull Rahim and Wan Mahmood, Wan Mohd. Asyraf and Tan, Yong Chee and Nik Malek, Nik Ahmad Nizam and Jemon, Khairunnadwa and Sathishkumar, Palanivel (2022) Curcumin-loaded electrospun poly(ɛ-caprolactone) nanofibrous membrane: an efficient and biocompatible wound-dressing material. Materials Letters, 315 (NA). pp. 1-5. ISSN 0167-577X
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Official URL: http://dx.doi.org/10.1016/j.matlet.2022.131910
Abstract
The present study aims to produce a natural drug-incorporated nano-based wound-dressing material with high biocompatibility and enhanced antibacterial efficacy for promoting rapid wound healing. Electrospun curcumin-loaded poly(ɛ-caprolactone) (PCL/Cur) membrane is successfully fabricated and characterized using standard techniques. The fabricated PCL/Cur membrane showed a higher antibacterial effect against the bacterial strains, Staphylococcus aureus and Escherichia coli; whereas, a very less cytotoxic effect was observed on the mouse fibroblast (L929) cells. This study concludes that PCL/Cur membrane could be a simple, biocompatible, and efficient material for wound-dressing applications.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | antibacterial activity, curcumin, electrospun membrane, Poly(ɛ-caprolactone), wound-dressing material |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Science |
| ID Code: | 103008 |
| Deposited By: | Yanti Mohd Shah |
| Deposited On: | 12 Oct 2023 08:46 |
| Last Modified: | 12 Oct 2023 08:46 |
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